Unlu G, Millet A, Wangdu K, Donné R, Erdal R, DelGaudio NL, Uygur B, Shah V, Cho K, Fecke A, Cansiz F, Tarcan ZC, Viscio MI, Kilic E, Kurth I, Terry AR, Romesser PB, Molina H, Sickmann A, Basturk O, Patti GJ, Beyaz S, Smith KW, Lujambio A, Tasdogan A, Tavazoie SF and Birsoy K (2026) Mitochondrial profiling links tumor genotype to metabolic and immune vulnerabilities in liver cancer, in press, Science. https://www.biorxiv.org/content/10.1101/2025.09.10.675369v1

Khan A, Yen FS*, Unlu G*, DelGaudio NL*, Erdal R, Xiao M, Wangdu K, Cho K, Gamazon ER, Patti GJ, and Birsoy K (2025) Machine learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis, Cell Metabolism. 37(11):2220-2232.e8. PMID: 41075780. https://www.cell.com/cell-metabolism/fulltext/S1550-4131(25)00434-6

Soula M, Unlu G, Welch R, Chudnovskiy A, Uygur B, Shah V, Alwaseem H, Bunk P, Subramanyam V, Yeh H-W, Khan A, Heissel S, Goodarzi H, Victora GD, Beyaz S, Birsoy K (2024), Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer, Nature, 633 (8029): 451-458. PMID: 39112706. https://doi.org/10.1038/s41586-024-07787-1

Khan A, Unlu G, Lin P, Liu Y, Kilic E, Kenny TC, Birsoy K (2024) Metabolic gene function discovery platform GeneMAP identifies SLC25A48 as necessary for mitochondrial choline import. Nature Genetics. 56(8):1614-1623. PMID: 38977856 https://doi.org/10.1038/s41588-024-01827-2.

Unlu G, Prizer B, Erdal R, Yeh H-W, Bayraktar EC, Birsoy K (2022) Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability, Molecular Cell, 82:2832-2843. PMID: 35714613. https://doi.org/10.1016/j.molcel.2022.05.024

Unlu G, Qi X, Gamazon ER*, Melville DB*, Patel N*, Rushing AR, Hashem M, Al-Faifi A, Chen R, Li B, Alkuraya FS, Cox NJ, Knapik EW (2020) Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies, Nature Medicine, 26: 98-109. PMID: 31932796 https://doi.org/10.1038/s41591-019-0705-y